Signs and symptoms: Topically applied corticosteroids, including mometasone furoate, can be absorbed in amounts sufficient to produce systemic effects. Thus, its prolonged use or misuse (e.g., using the product more often than recommended, in skin with altered barrier, or on large areas of the body; use of occlusive dressings) for a longer period of time can suppress the HPA function resulting in secondary adrenal insufficiency, which is usually reversible. The growth and development of children may also be affected.
Treatment: No specific antidote is available for mometasone overdose. If you have used more than the recommended dosage, consult the doctor immediately. The use of appropriate symptomatic treatment is recommended. Electrolyte imbalance should be treated, if needed. If HPA axis suppression occurred, the doctor may attempt to withdraw the drug, reduce the frequency of application, or substitute a less potent steroid. In case of long-term toxicity, corticosteroid therapy should be withdrawn gradually.